Cyclopia - Wikipedia
A Swedish description from 1793 of a newborn with cyclopia. On 1 March 1793, a 46-year-old woman in Boalts Torp, Glimåkra, Sweden gave birth to a child with cyclopia that died after two hours.
Cyclopia - EyeWiki
Cyclopia (also known as synophthalmia or cyclocephaly) is a clinical abnormality where fusion of both eyes can be seen in a single, central orbit located in the middle of the face. It is the facial expression of the most severe form of a congenital anomaly …
Cyclopia: Understanding the Rare Congenital Malformation
2023年10月17日 · Cyclopia, also known as synophthalmia, is an extremely rare and severe congenital malformation characterized by the fusion of the eyes into a single midline eye structure. This condition is a result of abnormal embryological development and is typically associated with other severe birth defects.
Microphthalmos - EyeWiki
Microphthalmos also called microphthalmia, is a rare developmental disorder of the eye in which one or both eyes are abnormally small. It may occur as an isolated entity but is commonly associated with other ocular or systemic findings as part of a syndrome.
Differentiation of true anophthalmia from clinical anophthalmia …
2014年7月7日 · Anophthalmia is associated with many known syndromes. Clinical findings, as well as imaging modalities and genetic analysis, are important in making the diagnosis. Imaging modalities are crucial scanning methods. Cryptophthalmos, cyclopia, synophthalmia and congenital cystic eye should be considered in differential diagnoses.
Congenital Malformations, Orbit | SpringerLink
The term is commonly used to describe either the abnormality of true cyclopia, in which a single median eye is the only ocular structure present, or synophthalmia, in which two globes are partially fused in a median position.
Cyclopia - SpringerLink
2018年1月1日 · In true cyclopia, the fetus or infant presents with one central eye. The anterior brain and the midline structures do not develop normally. The result is a central cavity or pseudo-orbit with a proboscis but without a nasal cavity. In synophthalmia, the two globes are partially fused in the center.
Cyclopia: isolated and with agnathia–otocephaly complex
2017年8月30日 · AOC (also known as agnathia–microstomia–synotia syndrome) is a rare lethal congenital malformation of the first branchial arch characterised by the association of agnathia (agenesis of mandible) or mandibular hypoplasia, melotia (anteromedial malposition of ears), microstomia (small mouth), aglossia or microglossia (absent or rudimentary tongue).
The Malformed Eye - SpringerLink
2013年1月1日 · Histologically, synophthalmia can show two eyes with varying degrees of fusion with a spectrum of appearances ranging from relatively normal intrinsic ocular structures to totally anomalous.
Cyclopia syndrome - BMJ Case Reports
Cyclopia (also cyclocephaly or synophthalmia) is a rare form of holoprosencephaly and is a congenital disorder (birth defect) characterised by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities.