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  1. National Geographic
    https://www.nationalgeographic.com › science › article › untangling-mysteries-of-the-brain...

    Untangling mysteries of the brain—with the …

    • Squid's giant nerve fibers have been essential to research for decades. Now breakthroughs in editing squid genomes could lead to a more complete understanding of nervous systems in general.… 展开

    Big squid axons

    A few hours later, I see what Rosenthal means as Pablo Miranda Fernandez, a neuroscientist from the National Institutes of Health, takes one of the squid from the Skipjack up to hi… 展开

    National Geographic
    Tunable genetics

    Other squid nerves from the Skipjack catch will be used by Rosenthal to study the animal’s curious ability to alter genetic information in RNA molecules within their nerve cells at ver… 展开

    National Geographic
    Cephalopod Operation

    The first hurdle was sequencing Doryteuthis pealeii’s genome, which the team needed in order to know where to make the cut, says Marine Biological Laboratory neur… 展开

    National Geographic
    Squid culture

    Despite these advances in Dorytheuthis pealeii research, and the distinguished career of the species in service of science, the squid has a serious drawback as a genetic researc… 展开

    National Geographic
    Can a squid brain be mapped?
    This is an electron microscope, revealing a miraculous map of neurons within that slice of squid brain. By imaging animal brains in infinitesimal detail, researchers hope to uncover the secrets of brain structure, and how we are able to change in response to our environment. The potential benefits of such ‘brain roadmaps’ are huge.
    cam.ac.uk
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    目录
    Big squid axons
    Tunable genetics
    Cephalopod Operation
    Squid culture
    Can a squid brain be mapped?
     
  1. Squid stellate ganglia contain the largest nerve cells on the planet, which gave early neuroscientists their first glimpses into the inner workings of the brain and continue to be used in research today. They are part of the distributed nervous system that the squid uses to contract its mantle and to jet away from predators at tremendous speed.

    Squid Brains, Eyes, and Color | Gilly Lab

    gillylab.stanford.edu/neuroscience
    gillylab.stanford.edu/neuroscience
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    Can a squid brain be sliced?
    In a darkened lab in south Cambridge, a high-voltage gun is firing electrons through a squid brain. The brain has been sliced with a diamond knife to a thickness of 40 nanometres, far smaller than the width of a human hair. After being injected with heavy metals, the brain slice now resembles a mineral.

    The secrets of our brains - University of Cambridge

    cam.ac.uk
    Could editing squid genomes help us understand nervous systems?
    Squid's giant nerve fibers have been essential to research for decades. Now breakthroughs in editing squid genomes could lead to a more complete understanding of nervous systems in general. “We’ve got tuuuuuubes!” fisherman Matt Rissell shouts as he leans over the gunwale of the Skipjack to check his line.

    Untangling mysteries of the brain—with the remarkable biology of squid

    nationalgeographic.com
    Can a squid brain be mapped?
    This is an electron microscope, revealing a miraculous map of neurons within that slice of squid brain. By imaging animal brains in infinitesimal detail, researchers hope to uncover the secrets of brain structure, and how we are able to change in response to our environment. The potential benefits of such ‘brain roadmaps’ are huge.

    The secrets of our brains - University of Cambridge

    cam.ac.uk
    Can a squid have a see-through brain?
    And like other cephalopods, it has a relatively large and sophisticated brain. The see-through version is made possible by a gene editing technology called CRISPR, which became popular nearly a decade ago. Albertin and Rosenthal thought they might be able to use CRISPR to create a special squid for research.

    A transparent squid could reveal secrets of the brain - NPR

    npr.org
    Can a see-through squid help scientists understand cephalopods?
    Because it suggests that her see-through squid will help scientists understand not only cephalopods, but all living creatures. A see-through squid is giving scientists an unprecedented view of the brain and other organs in a living animal.

    A transparent squid could reveal secrets of the brain - NPR

    npr.org
    Why are squid photoreceptor neurons important?
    Being a very simple nervous system relatively easy to be manipulated experimentally and visualized by simple microscope or magnifying glass, the giant synapses at stellate ganglion and the large synaptosomes prepared from the squid photoreceptor neurons served as an attractive model to Histology and Anatomy studies.

    The Biological and Structural Organization of the Squid Brain - IntechO…

    intechopen.com
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  3. IntechOpen
    https://www.intechopen.com › chapters

    The Biological and Structural Organization of the Squid …

    2023年1月19日 · Here, the stellate ganglion and the large synaptosome from photoreceptor neurons were isolated from squid nervous system and showed a biological and structural organization of brain by biochemical and …

  4. harvard.edu
    https://news.harvard.edu › gazette › stor…

    Harvard study looks at how cephalopods develop their …

    2022年11月16日 · Researchers from the FAS Center for Systems Biology describe in a new study how they used a new live-imaging technique to watch neurons being created in squid embryos almost in real-time. They were then …

  5. Gilly Lab
    https://gillylab.stanford.edu › neuroscience

    Squid Brains, Eyes, and Color | Gilly Lab

    Squid stellate ganglia contain the largest nerve cells on the planet, which gave early neuroscientists their first glimpses into the inner workings of the brain and continue to be used in research today. They are part of the distributed nervous …

  6. Marine Biological Laboratory
    https://www.mbl.edu › news › untangling-mysteries...

    Untangling Mysteries of the Brain—With the Biology of Squid

  7. NPR
    https://www.npr.org › sections › health-sho…

    A transparent squid could reveal secrets of the brain

    2023年8月28日 · These experimental brain implants can restore speech to paralyzed patients. The transparent squid is a genetically altered version of the hummingbird bobtail squid, a species usually found in...

  8. University of Cambridge
    https://www.cam.ac.uk › stories › secret…

    The secrets of our brains - University of Cambridge

    In a darkened lab in south Cambridge, a high-voltage gun is firing electrons through a squid brain. The brain has been sliced with a diamond knife to a thickness of 40 nanometres, far smaller than the width of a human hair. After …

  9. Wu Tsai Neurosciences Institute
    https://neuroscience.stanford.edu › new…

    Q&A: Evolution of octopus and squid brains could …

    Ocean-dwelling, otherworldly, and intelligent, the bobtail squid possesses a brain that is complex yet very different from our own. This squishy, walnut-sized creature is a cephalopod (a group that includes octopuses, squids and …

  10. ScienceDaily
    https://www.sciencedaily.com › releases

    MRI-based mapping of the squid brain - ScienceDaily

  11. Nature
    https://www.nature.com › articles

    A CRISPR first produces squid as clear as glass - Nature

    2020年7月31日 · The creation of spotless cephalopods hints that squid could make a good model organism for applying CRISPR to brain research. A longfin inshore squid hatchling treated with CRISPR gene...