Hypoxic–ischaemic brain injury (HIBI) is the main cause of prolonged or permanent neurological impairment and poor neurological outcomes in patients post-cardiac arrest (CA). CA causes an extensive brain injury of variable degree whose outcomes vary from complete recovery to severe disability or dea...

Hypoxic-ischemic brain injury encompasses a complex constellation of pathophysiological and cellular brain injury induced by hypoxia, ischemia, cytotoxicity, or combinations of these mechanisms and can result in poor outcomes including significant changes in personality and cognitive impairments in ...

Hypoxic-ischemic brain injury is a well known consequence of cardiac arrest. Variable injuries can occur with purely hypoxic or histotoxic insults such as asphyxiation and carbon monoxide poisoning. The injury may happen at the time of the insult, but there may also be continued damage after circula...