Tartrate-resistant acid phosphatase - Wikipedia
网页Tartrate-resistant acid phosphatase (TRAP or TRAPase), also called acid phosphatase 5, tartrate resistant (ACP5), is a glycosylated monomeric metalloprotein enzyme expressed in mammals. [5] It has a molecular weight of approximately 35kDa, a basic isoelectric point (7.6–9.5), and optimal activity in acidic conditions.
Tartrate-Resistant Acid Phosphatase - Health Encyclopedia
网页This test looks for the chemical tartrate-resistant acid phosphatase (TRAP) in your blood. This test can also be done on bone marrow. TRAP can appear in your blood if you have hairy cell leukemia.
Tartrate-Resistant Acid Phosphatase - an overview - ScienceDirect
网页Tartrate-Resistant Acid Phosphastae. Plasma levels of the tartrate-resistant acid phosphatase (pTRAP) are significantly elevated in patients with PHPT compared to healthy controls (98–100). In untreated patients, pTRAP levels correlate both with sTAP and uOHP, but also with serum PTH concentrations (101).
Role of tartrate-resistant acid phosphatase (TRAP) in long bone ...
网页Tartrate resistant acid phosphatase (TRAP) was shown to be critical for skeleton development, and TRAP deficiency leads to a reduced resorptive activity during endochondral ossification resulting in an osteopetrotic phenotype …
Acid phosphatases - PMC - National Center for Biotechnology …
网页One particular example is tartrate resistant acid phosphatase, which is detected in the serum in raised amounts accompanying pathological bone resorption. This article seeks to explore the identity and diversity of APs, and to demonstrate the relation between APs, human disease, and clinical diagnosis.
Tartrate-resistant acid phosphatase (TRAP) and the …
网页Tartrate-resistant acid phosphatase (TRAP), once considered to be just a histochemical marker of osteoclasts is now recognised to be a molecule of widespread occurrence with functions in both the skeleton and the immune system.
Biology and Clinical Significance of Tartrate-Resistant Acid ...
网页2009年11月14日 · Type 5 tartrate-resistant acid phosphatase (TRAP) has been a clinically relevant biomarker for about 50 years. It has always been a reliable and specific cytochemical marker for hairy cell leukemia and for differentiated cells of monocytic lineage.
Tartrate-Resistant Acid Phosphatase as a Biomarker of Bone
网页2017年6月17日 · Tartrate-resistant acid phosphatase (TRACP) is an enzyme abundantly expressed in tissues such as the bone, spleen, liver, lungs, and skin. It has two isoforms, namely, TRACP 5a and TRACP 5b.
网页5¢-flanking region of the mouse tartrate-resistant acid phosphatase provide insight for the improvement of therapeutic manage-gene. J Bone Miner Res1993; 8: 1263–1270. ment.
Tartrate-Resistant Acid Phosphatase - ScienceDirect Topics
网页Tartrate-resistant acid phosphatase (TRACP) is a lysosomal enzyme [183,184] composed of two isoforms in the circulation, TRACP5a found in activated macrophages and TRACP5b derived from osteoclasts. During bone resorption, TRACP5b is secreted by osteoclasts and generates reactive oxygen species.