Selexipag - Wikipedia
网页Selexipag, sold under the brand name Uptravi, is a medication developed by Actelion for the treatment of pulmonary arterial hypertension (PAH). [3] [4] Selexipag and its active metabolite, ACT-333679 (or MRE-269, the free carboxylic acid), are agonists of the prostacyclin receptor, which leads to vasodilation in the pulmonary circulation. [5]
Selexipag for the Treatment of Pulmonary Arterial Hypertension
网页2015年12月24日 · In a phase 2 trial, selexipag, an oral selective IP prostacyclin-receptor agonist, was shown to be beneficial in the treatment of pulmonary arterial hypertension. In this event-driven, phase 3,...
Selexipag: MedlinePlus Drug Information
网页Selexipag is used in adults to treat pulmonary arterial hypertension (PAH, high blood pressure in the vessels that carry blood to the lungs) to slow down the worsening of symptoms and reduce the chance of being hospitalized for PAH.
Selexipag: Uses, Interactions, Mechanism of Action - DrugBank …
网页Selexipag is a selective prostacyclin (IP, also called PGI2) receptor agonist. The key features of pulmonary arterial hypertension include a decrease in prostacyclin and prostacyclin synthase (enzyme that helps produce prostacyclin) in the lung.
Treatment with UPTRAVI® | UPTRAVI® (selexipag)
网页Learn about UPTRAVI® (selexipag) for treatment in adults. See full Prescribing and Safety Information.
Selexipag (Oral Route) Description and Brand Names - Mayo Clinic
网页2024年10月1日 · Selexipag is used to treat symptoms of pulmonary arterial hypertension, which is high blood pressure in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs.
Uptravi: Uses, Dosage, Side Effects, Warnings - Drugs.com
网页2023年10月24日 · Generic name: selexipag (oral/injection) [ se-LEX-i-pag ] Drug class: Agents for pulmonary hypertension. Medically reviewed by Judith Stewart, BPharm. Last updated on Oct 24, 2023. Uses; Warnings; Before taking; Dosage; Side effects; Interactions; FAQ; What is Uptravi?
Selexipag oral/injection Uses, Side Effects & Warnings - Drugs.com
网页2023年9月28日 · Selexipag is used to treat pulmonary arterial hypertension (PAH). Selexipag helps keep your condition from getting worse and helps lower your risk of needing to be hospitalized for PAH. Selexipag may also be used for purposes not listed in this medication guide.
Uptravi (selexipag) dosing, indications, interactions, adverse …
网页Medscape - Pulmonary arterial hypertension dosing for Uptravi (selexipag), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and...
Selexipag Monograph for Professionals - Drugs.com
网页2023年3月27日 · Selexipag (Monograph) Brand name: Uptravi. Drug class: Vasodilating Agents, Miscellaneous. Chemical name: 2- [4- [ (5,6-diphenylpyrazin-2-yl)-propan-2-yl-amino]butoxy]-N-methylsulfonylacetamide. Molecular formula: C 26 H 32 N 4 O 4 S. CAS number: 475086-01-2. Medically reviewed by Drugs.com on Mar 27, 2023. Written by …