Phenazocine - Wikipedia
网页Phenazocine (brand names Prinadol, Narphen) is an opioid analgesic drug, which is related to pentazocine and has a similar profile of effects. [2] Effects of phenazocine include analgesia and euphoria, also may include dysphoria and hallucinations at high doses, most likely due to action at κ-opioid and σ receptors. [3]
Phenazocine: Uses, Interactions, Mechanism of Action - DrugBank …
网页2017年6月23日 · Phenazocine may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone. Hydroflumethiazide: The therapeutic efficacy of Hydroflumethiazide can be decreased when used in combination with Phenazocine. Hydromorphone: The risk or severity of adverse effects can be increased when …
Phenazocine - an overview | ScienceDirect Topics
网页Phenazocine (Fig. 4) is a first-generation benzomorphan-based analgesic. It was first synthesized by Eddy, May, and Ager in 1959 [127–129]. Phenazocine was 20 times more potent than morphine and 70 times more potent than its (+)-isomer in eliciting analgesia in mice in a hot plate test [127].
Phenazocine - a strong analgesic | Drug and Therapeutics Bulletin
网页Phenazocine (Narphen - SNP) is an analgesic comparable to morphine, morphine-like analgesics and pentazocine 1 and was introduced into clinical practice about 10 years ago for the treatment of chronic pain and in terminal disease. It has also been used for obstetric and post-operative pain.
Phenazocine | C22H27NO | CID 14707 - PubChem
网页Phenazocine | C22H27NO | CID 14707 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
PHENAZOCINE - National Center for Advancing Translational …
网页(-)-Phenazocine is an opioid analgesic drug, which is related to pentazocine and has a similar profile of effects. (-)-Phenazocine is a potent mu opioid receptor agonist. In addition, (−)-phenazocine is also known to bind to δ opioid receptors (DOR) and κ …
Phenazocine Overview - Active Ingredient - RxReasoner
网页Phenazocine is an opioid analgesic drug, which is related to pentazocine and has a similar profile of effects. Effects of phenazocine include analgesia and euphoria, also may include dysphoria and hallucinations at high doses, most likely …
Phenazocine | The Merck Index Online - Royal Society of Chemistry
网页2017年5月7日 · Phenazocine Molecular formula C 22 H 27 NO Molecular weight 321.46 Percent composition C 82.20%, H 8.47%, N 4.36%, O 4.98% Standard InChI InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19(24)15-20(18)22(16,2)11-13-23(21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3/t16-,21+,22+/m0/s1 Standard InChIKey …
Phenazocine - NIST Chemistry WebBook
网页2017年5月7日 · Phenazocine. Formula: C 22 H 27 NO. Molecular weight: 321.4559. IUPAC Standard InChI: InChI=1S/C22H27NO/c1-16-21-14-18-8-9-19 (24)15-20 (18)22 (16,2)11-13-23 (21)12-10-17-6-4-3-5-7-17/h3-9,15-16,21,24H,10-14H2,1-2H3. IUPAC Standard InChIKey: ZQHYKVKNPWDQSL-UHFFFAOYSA-N. CAS Registry Number: 127-35-5. …
3. The Progresses of Biosynthetic Pathways of Phenazines
网页2021年10月27日 · Abstract. Phenazines are a large group of nitrogen-containing heterocycles, providing diverse chemical structures and various biological activities. Natural phenazines are mainly isolated from marine and terrestrial microorganisms.