Myeloid tissue - Wikipedia
In hematopoiesis, myeloid cells, or myelogenous cells are blood cells that arise from a progenitor cell for granulocytes, monocytes, erythrocytes, or platelets [1] [2] (the common myeloid progenitor, that is, CMP or CFU-GEMM), or in a narrower sense also often used, specifically from the lineage of the myeloblast (the myelocytes, monocytes, and ...
What are Progenitor Cells? Exploring Neural, Myeloid and …
2024年1月24日 · Myeloid progenitor cells are precursors to the following types of blood cells: Red blood cells/erythrocytes; Platelets; Mast cells; Osteoclasts; Granulocytes; Monocyte-macrophages; Dendritic cells; Lymphoid progenitor cells (also known as lymphoblasts) are precursors to other mature blood cell types, including: T-cells/T-lymphocytes; B-cells/B ...
Heterogeneity and origins of myeloid cells - PMC - National …
2022年7月7日 · Consideration of the heterogeneity of myeloid cells is critical for understanding their diverse activities, such as the role of macrophages in tissue damage versus repair, or tumor growth versus elimination. Insights into these mechanisms are informing the design of novel therapeutic approaches.
Myeloid Progenitor Cell - an overview | ScienceDirect Topics
Myeloid progenitor cells are the precursors of red blood cells, platelets, granulocytes (polymorphonuclear leukocytes [PMNs]: neutrophils, eosinophils, and basophils), monocyte-macrophages, dendritic cells (DCs), and mast cells and osteoclasts.
Hematopoietic progenitor cells as integrative hubs for ... - Nature
2019年6月18日 · MPPs differentiate into oligo-potent or uni-potent progenitor cells, such as common myeloid progenitors (CMPs), granulocyte–monocyte progenitors (GMPs) and others, which give rise to mature...
Biology and relevance of human acute myeloid leukemia stem cells
2017年3月23日 · Acute myeloid leukemia (AML) is a rapidly progressing hematopoietic malignancy, characterized by the accumulation of clonal myeloid progenitor cells arrested in their ability to differentiate into mature blood cells that is accompanied by multilineage cytopenias. 1 Indeed, it is the lack of normal cells, including red blood cells, platelets, and...
Myeloid Cell Origins, Differentiation, and Clinical Implications
The hematopoietic lineage is divided into two main branches: the myeloid and lymphoid arms. The myeloid arm is characterized by the common myeloid progenitor and all of its resulting cell types. The stages of hematopoiesis have been defined in both mice and humans.
Dynamics of Human Hematopoietic Stem and Progenitor Cell ...
Myeloid progenitor cells, endothelial cells: Myeloid cell differentiation: CD117: c-KIT, stem cell factor receptor (SCFR), PBT ... Brovall C, Fackler MJ, Schwartz JF, Shaper JH. Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J Immunol. 1984 ...
Distinct myeloid progenitor–differentiation pathways ... - Nature
2016年4月4日 · By single-cell transcriptome profiling of pre-GMs, we identified distinct myeloid differentiation pathways: a pathway expressing the gene encoding the transcription factor GATA-1 generated mast...
NPM1-fusion proteins promote myeloid leukemogenesis through …
5 天之前 · NPM1::CCDC28A-expressing cells were enriched in a ckit + granulocytic-monocytic progenitor (GMP)-like population known to contain leukemia stem cells, whereas NPM1::MLF1-expressing cells produced ...