Hepatic lipase - Wikipedia
网页Hepatic lipase (HL), also called hepatic triglyceride lipase (HTGL) or LIPC (for "lipase, hepatic"), is a form of lipase, catalyzing the hydrolysis of triacylglyceride. Hepatic lipase is coded by chromosome 15 and its gene is also often referred to as HTGL or LIPC. [5]
Lipase Blood Test: What It Is & Understanding the Results
网页2024年7月16日 · A lipase blood test shows how much of the enzyme lipase you have in your blood. Your pancreas makes most of your body’s lipase. Extremely high levels (three or more times the normal range) may signal acute pancreatitis or other pancreatic disorders.
Hepatic lipase:structure/function relationship, synthesis,and ...
网页2002年8月1日 · Hepatic lipase (HL) is a lipolytic enzyme, synthesized by hepatocytes and found localized at the surface of liver sinusoid capillaries. In humans, the enzyme is mostly bound onto heparan-sulfate proteoglycans at the surface of hepatocytes and also of sinusoid endothelial cells.
Biochemistry, Lipase - StatPearls - NCBI Bookshelf
网页2023年6月26日 · Hepatic lipase plays a crucial role in developing and delivering low-density lipoprotein (LDL). The LDL is formed by modifying the IDL in the peripheral tissue and liver by hepatic lipase. These LDL particles are taken up, or endocytosed, via receptor-mediated endocytosis by target cell tissue.
Hepatic Lipase, High Density Lipoproteins, and Hypertriglyceridemia
网页Hepatic lipase (HL) is a lipolytic enzyme that contributes to the regulation of plasma triglyceride (TG) levels. Elevated TG levels may increase the risk of developing coronary heart disease, and studies suggest that mutations in the HL gene may be associated with elevated TG levels and increased risk of coronary heart disease. Hepatic lipase ...
Hepatic Lipase - an overview | ScienceDirect Topics
网页Hepatic lipase (HL) is an endothelial-bound enzyme synthesized and secreted from hepatocytes that catalyzes the hydrolysis of TG and phospholipids in several lipoproteins. HL is involved in the remodeling of apo B-containing lipoproteins and HDL, and in the production of small, dense LDL, as well as small HDL remnants.
The Role of Metabolic Lipases in the Pathogenesis and …
网页2020年9月28日 · This review will focus on specific functions of intracellular lipases in lipid partitioning, covering basic and translational findings in the context of liver disease. In addition, the clinical relevance of genetic mutations in human disease and potential therapeutic opportunities will be discussed. Abbreviations. ALD.
Hepatic lipase deficiency - MedlinePlus
网页Hepatic lipase deficiency is a disorder that affects the body's ability to break down fats (lipids). People with this disorder have increased amounts of certain fats, known as triglycerides and cholesterol, in the blood.
Hepatic Lipase - an overview | ScienceDirect Topics
网页Hepatic Lipase is an enzyme that is synthesized in the liver and is involved in the remodeling of various lipoproteins, such as chylomicron remnants, IDL, LDL, and HDL. It plays a role in reverse cholesterol transport and can influence lipoprotein metabolism by interacting with lipoprotein receptors.
Hepatic Lipase: a Comprehensive View of its Role on Plasma
网页Hepatic lipase (HL) is a key enzyme catalyzing the hydrolysis of triglycerides (TG) and phospholipids (PLs) in several lipoproteins. It is generally recognized that HL is involved in the remodeling of remnant, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and the production of small, ….
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