A co-receptor is a cell surface receptor that binds a signalling molecule in addition to a primary receptor in order to facilitate ligand recognition and initiate biological processes, such as entry of a pathogen...
en.wikipedia.org/wiki/Co-receptorCD4 and CD8 molecules are known as Co-receptors. The T cells recognise and bind peptide antigens only when they are presented in combination (complex) with MHC molecule. T cells not only recognise the peptide...
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A co-receptor is a cell surface receptor that binds a signalling molecule in addition to a primary receptor in order to facilitate ligand recognition and initiate biological processes, such as entry of a pathogen into a host cell. 展开
The term co-receptor is prominent in literature regarding signal transduction, the process by which external stimuli regulate internal cellular functioning. The key to optimal cellular … 展开
CD family
The CD family of co-receptors are a well-studied group of extracellular receptors found in immunological cells. The CD receptor family typically act as co-receptors, illustrated by the classic example of 展开Depending on the type of ligand a co-receptor binds, its location and function can vary. Various ligands include interleukins, neurotrophic factors, fibroblast growth factors 展开
Because of their importance in cell signaling and regulation, co-receptors have been implicated in a number of diseases and disorders. … 展开
Currently, the two most prominent areas of co-receptor research are investigations regarding HIV and cancer. HIV research is highly focused on the adaption of HIV strains to a variety of host … 展开
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网页co-receptor 定 义 能够协助受体与其配体特异结合并引起生物效应的膜蛋白。如帮助辅助T淋巴细胞与抗原提呈细胞黏附的CD4等。 应用学科 生物化学与分子生物学（一级学科）， …
Co-Receptor - an overview | ScienceDirect Topics
网页45 行 · A co-receptor in the context of Neuroscience refers to an accessory receptor on the cell surface that indirectly regulates signaling by binding to the ligand and initiating …
Co-Receptors: Function | British Society for Immunology
网页The activation of specialised immune cells from the adaptive immune response (i.e. B cells and T cells) is controlled by their specific antigen receptor but also by co-receptors. T cell co-receptors. In order to be …
Co-Receptors and Recognition of Self at the Immunological Synapse
网页The co-receptors CD4 and CD8 are important in the activation of T cells, primarily because of their ability to interact with the proteins of the MHC, enhancing recognition of the …
Molecular mechanisms of T cell co-stimulation and co …
网页2013年3月8日 · Co-stimulatory and co-inhibitory receptors have a pivotal role in T cell biology, as they determine the functional outcome of T cell receptor (TCR) signalling.
B-cell co-receptors: The two-headed antigen - Cell Press
网页In both T cells and B cells, the complexed antigen can bind not only the antigen receptor, but also a second cell-surface receptor referred to as the co-receptor. The complexed antigen brings together the antigen …
Cell-surface co-receptors: emerging roles in signaling …
网页Signaling co-receptors modulate the ligand binding and signaling of their respective signaling receptors. In recent years, roles for co-receptors have expanded to include essential functions in morphogen gradient …
A comprehensive review on the role of co-signaling receptors
网页Co-stimulatory and co-inhibitory receptors, collectively known as co-signaling receptors, play an indispensable role in the regulation of Teff and Treg cell expansion and function …
How the Signaling Crosstalk of B Cell Receptor (BCR) …
网页2021年3月24日 · Taken together, our studies present a new concept that may better explain how signaling components of the BCR and co-receptor pathways assure robust humoral immune responses while …
