Basement membrane - Wikipedia
The basement membrane, also known as base membrane, is a thin, pliable sheet-like type of extracellular matrix that provides cell and tissue support and acts as a platform for complex signalling. [ 1 ] [ 2 ] The basement membrane sits between epithelial tissues including mesothelium and endothelium , and the underlying connective tissue.
Basement Membrane: What Is It, How It’s Formed, and More
2022年9月14日 · The basement membrane, also known as basal lamina, is a thin, dense layer of extracellular matrix that lines most human tissues forming the supporting structure and scaffolding for epithelial tissue and separates different types of cells, such as nerve cells and muscle cells
Basement membrane: Anatomy and function - Kenhub
2023年10月30日 · The basement membrane is a thin, non-cellular, extracellular protein matrix that forms a specialized supporting sheet directly beneath the basal surfaces of all epithelial cells, separating them from underlying supporting tissues.
The nature and biology of basement membranes - PMC
Basement membranes (BMs) are cell-adherent extracellular matrices widely distributed in metazoan tissues. First identified in skeletal muscle 176 years ago [1], elucidation of BM constituents, structure, functions and genetics has required advances in multiple fields stretched over many years.
Basement membranes in development and disease - PMC
Basement membranes provide an adhesive substrate for cells, and they are linked functionally to the actin cytoskeleton via integrins or other ECM receptors to mediate cell attachment and migration, as well as modulating intracellular signaling pathways.
Basement membranes: Current Biology - Cell Press
2017年3月20日 · Basement membranes (BMs) are thin, dense sheets of specialized, self-assembled extracellular matrix that surround most animal tissues (Figure 1, top). The emergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were essential for the formation of tissues.
The role of basement membranes in cardiac biology and disease
2021年8月8日 · Basement membranes (BMs) are highly specialised extracellular matrix (ECM) structures that within the heart underlie endothelial cells (ECs) and surround cardiomyocytes and vascular smooth muscle cells.
The nature and biology of basement membranes - PubMed
Basement membranes are delicate, nanoscale and pliable sheets of extracellular matrices that often act as linings or partitions in organisms. Previously considered as passive scaffolds segregating polarized cells, such as epithelial or endothelial cells, from the underlying mesenchyme, basement memb ….
To form and function: on the role of basement membrane
The basement membrane (BM) is a special type of extracellular matrix that lines the basal side of epithelial and endothelial tissues. Functionally, the BM is important for providing physical and biochemical cues to the overlying cells, sculpting the tissue into its correct size and shape.
Structure and function of basement membranes - PubMed
Abstract. Basement membranes (BMs) are present in every tissue of the human body. All epithelium and endothelium is in direct association with BMs. BMs are a composite of several large glycoproteins and form an organized scaffold to provide structural support to the tissue and also offer functional input to modulate cellular function.
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