Adolescent rats engage the orbitofrontal-striatal pathway …
网页2024年4月13日 · We investigated the role of OFC–DMS in response inhibition in adolescent and adult rats. We observed a causal and age-dependent relationship in OFC projections to DMS, and pronounced age ...
The Laboratory Rat: Relating Its Age With Human's - PMC
网页2012年9月9日 · During the first 6 years of human life, appearance of ossific centers are observed mainly in the bones of the humerus, femur, tibia, radius, patella and ulna. In addition, closures of epiphyseal plates are an indicator of the adolescent period.
Reinforcement Learning during Adolescence in Rats - PMC
网页2020年7月7日 · Here, we describe a novel behavioral protocol for rapidly assessing adaptive choice behavior in adolescent rats with a reversal-learning paradigm. Using a computational approach, we demonstrate that age-related changes in reversal-learning performance in male and female Long–Evans rats are linked to specific reinforcement-learning mechanisms ...
Acute and long-term effects of adolescence stress exposure on …
网页2023年8月23日 · Adolescent stress models were biological, such as cortisol or cytokine injections, and behavioural paradigms, including social defeat, isolation and chronic mild stress in either rats or mice...
网页the neural networks that subserves impulsivity in adolescents, we used a reward‑guided behavioral model that quanties age dierences in impulsive actions in adult and adolescent rats of both...
The immune system has a say in how hard ‘teen’ rats play
网页2018年11月6日 · These results suggest that by chewing up D1 receptors, the brain’s immune system transforms adolescent male rats into chilled-out adults. Kopec and her team published their findings September 25 in Nature Communications .
Neural activation associated with outgroup helping in adolescent rats
网页2022年6月17日 · Adolescents rats — but not adult rats — helped outgroup members, releasing them from a trap • Neural activity was higher for ingroup members across some regions independent of age • Activity was modulated by age in the insula, hippocampus, hypothalamus, and vOFC • Adolescent “non-openers” showed …
Stress vulnerability during adolescent development in rats
网页This study tests the hypothesis that adolescent development is a stage of enhanced vulnerability to chronic stress. Male Sprague-Dawley rats were exposed to our 14-d chronic variable stress (CVS) paradigm at three developmental stages: 1) early adolescence (35 d; age at initiation of CVS); 2) late adolescence (50 d); or 3) adulthood (80 d).
Handling of adolescent rats improves learning and memory …
网页Here we examined the effects of handling on memory and anxiety levels of adolescent rats. Male Sprague-Dawley rats (age, 60 d) were divided into a control group and a handled group, which were handled for 5 min daily, 5 d per week, for 6 wk.
Social Behavior and Social Motivation in Adolescent Rats
网页1999年10月1日 · Adolescent rats were able to modify their social behaviors in response to social activity of the play partner: in isolated animals exposed to low socially active group-housed partners, play behavior was transformed into social activities unrelated to play; exposure of group-housed adolescents to high socially active previously isolated partners ...