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In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula R−C(=O)−NR′R″, where R, R', and R″ represent any group, typically organyl groups or hydrogen atoms. The amide group is called a peptide bond when it is part of the main chain of a protein, and an … 展开
The core −C(=O)−(N) of amides is called the amide group (specifically, carboxamide group).
In the usual nomenclature, … 展开The lone pair of electrons on the nitrogen atom is delocalized into the Carbonyl group, thus forming a partial double bond between nitrogen and … 展开
From carboxylic acids and related compounds
Amides are usually prepared by coupling a carboxylic acid with … 展开Amides do not readily participate in nucleophilic substitution reactions. Amides are stable to water, and are roughly 100 times more stable towards 展开
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The Amide Functional Group: Properties, Synthesis, and …
网页2018年2月28日 · A primary (1°) amide has nitrogen attached to a single carbon; a secondary (2°) amide has the nitrogen attached to two carbons; a tertiary (3°) amide has …
21.7 Chemistry of Amides - Organic Chemistry - OpenStax
网页Proteins, nucleic acids, and many pharmaceutical agents have amide functional groups. The reason for this abundance of amides is that they are stable in the aqueous conditions …
酰胺 - 百度百科
网页英文将羧酸的词尾-ic acid改-amide。 氨的氮原子上连有三个氢，一个氢被酰基取代称为单酰胺，两个氢或三个氢被取代的称为二酰胺或三酰胺。 英文用di、tri表示二、三加在羧酸的英文名称前。
21.7: Chemistry of Amides - Chemistry LibreTexts
网页Amides are most commonly prepared though the reaction of an acid chloride with ammonia, a 1 o amine, or 2 o amine. In an analogous reaction, an amide can be prepared through …
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24.1: Structural, Physical, and Spectral Characteristics of …
网页2021年7月31日 · Primary amides have two \(\ce{N-H}\) bands of medium intensity near \(3500 \: \text{cm}^{-1}\) and \(3400 \: \text{cm}^{-1}\), whereas secondary amides, to a first approximation, have only one \(\ce{N-H}\) …
Amide (functional group) - Wikipedia
网页In chemistry, the term amide (/ ˈ æ m aɪ d / or / ˈ æ m ɪ d / or / ˈ eɪ m aɪ d /) [1] [2] [3] is a compound with the functional group R n E(=O) x NR 2, where x is not zero, E is some …
Efficient synthesis of primary and secondary amides via ... - Nature
网页2021年10月13日 · The p-, m-, and o-methyl-substituted methyl benzoate participate in the reactions to produce the corresponding primary amides (2–4), and a good yield can be …
Rethinking amide bond synthesis - Nature
网页2011年12月21日 · It involves activation of a carboxylic acid by an activating group (A*), followed by nucleophilic displacement by a free amine to generate a new amide bond in …
