Biologics License Application currently under review by U.S. FDA; PDUFA goal date of December 28, 2024WALTHAM, Mass., Sept.

Similarly, the universities portfolio in Preclinical comprises 2 molecule. CD40 ligand or CD40L is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily.

One possible strategy for the treatment of T1D is to stimulate the regulatory arm of the immune response, i.e. to promote the function of tolerogenic dendritic cells (tolDC) and regulatory T cells ...

Findings from the international FORT-2 clinical trial showed that a combination treatment including immunotherapy is safe and ...

How can molecular structures be analyzed when the resolution of the techniques available is not sufficient? Researchers from ...

Thus, NK cells recognize and kill tumor cells even if, due to a tumor-escape strategy on tumor cells, ligand expression for the CAR receptor is downregulated. [52] In Hodgkin lymphoma, in which the ...

In pre-clinical cancer models, the combination of FGFR inhibitor and a programmed cell death ligand 1 (PD-L1) inhibitor showed increased survival and antitumor activity, suggesting clinical utility of ...

a Nuffield Department of Orthopaedic Surgery, University of Oxford, Oxford, b Department of Pathology, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford OX3 7LD OBJECTIVE Osteoprotegerin ...

Immune checkpoint inhibitors are the superheroes of cancer therapy. | Immune checkpoint inhibitors are the superheroes of ...

Pulmonary fibrosis (PF), scarring of tissue surrounding tiny air sacs called alveoli, can result in life-threatening ...