plus robust 5’-to-3’ exonuclease activity of Exo1 chewing away. This resection is a conserved feature of recombination but remains poorly understood. We developed a next-generation-sequencing method ...
To delineate the ligase-DNA interface, we footprinted the ligase binding site on DNA. The size of the exonuclease III footprint of ligase bound to a single nick in duplex DNA is 19 to 21 nucleotides.