The ERBB receptors are a group of receptor tyrosine kinases (RTKs) involved in key cellular functions including cell growth and survival. What are the activation mechanisms particular to ERBBs?

随着 EGFR-TKI 更新迭代，EGFR 突变非小细胞肺癌（NSCLC）患者的生存状况得到了极大改善。然而，这些患者面临着更高的脑转移风险，且脑转移一旦发生，其预后通常不容乐观。FLAURA2 研究凭借着显著的无进展生存期（PFS）获益，开启了 ...

GlobalData’s report assesses the drugs in the Tyrosine Protein Kinase Receptor UFO pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development ...

Insulin resistance plays a role in many diseases. The new research provides insights into why insulin resistance appears to ...

We are also actively investigating the regulation of Syk tyrosine kinase binding to membrane immune receptors and other signaling proteins. Syk recognizes doubly phosphorylated regions of the receptor ...

本次ESMO大会进一步更新报道了中国桥接研究的数据。这项Ⅱ期研究招募了对伊马替尼治疗失败或不耐受的GIST成年患者，随机（1:1）接受瑞派替尼150 mg每日一次（QD）或舒尼替尼50 mg ...

随着靶向、免疫等治疗手段的兴起，晚期胃癌的一线治疗手段日益丰富，然而二线治疗领域却长期面临研究进展缓慢、治疗选择有限的困境。而 FRUTIGA ...

GlobalData’s report assesses the drugs in the Tyrosine Protein Phosphatase Non Receptor Type 11 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the ...

Sumit Sharma, MD, sat down with Sydney Crago of Modern Retina to discuss his presentation on the 3 tyrosine kinase inhibitors ...

Mental sharpness, focus, the ability to get more done in less time; people are increasingly desperate for all of these things ...