除了mRNA疫苗外，T7 RNA聚合酶还被广泛应用于其他核酸药物的体外合成。这些核酸药物包括反义RNA、siRNA（小干扰RNA）、miRNA（微小RNA）等，它们通过特定的机制在细胞内发挥治疗作用。T7 RNA聚合酶能够高效地催化这些核酸药物的合成 ...

通过利用RNAse H酶特异性地降解与DNA探针杂交的RNA区域，TREX技术不仅可以揭示已知的RNA-蛋白质相互作用，还能发现新的、未被发现的相互作用。

为了研究RNA Pol II 和转录因子结合的解离动力学，作者使用新型基因工程方法、成像工具和更为特异的抑制剂对果蝇多染色体进行了活细胞成像。 RNA聚合酶II (RNA Pol II) 介导的转录是一个高度调控的多步骤过程，负责产生所有mRNA，在不同的步骤中由蛋白质复合物 ...

研究人员进行了体内实验以评估IMT1的抗肿瘤效果。每只小鼠皮下注射700万个pCan1原代细胞，3周后形成pCan1异种移植瘤，每个细胞接近100 mm3，记为“第0天”。在裸鼠移植瘤模型中，IMT1以50 mg/kg口服给药，在第0天和第3天给药2个周期。肿瘤生长曲线显示IMT1显著抑制pCan1异种移植瘤的生长。pCan1异种移植瘤的日生长速度 (以mm / ...

STONY BROOK, NY / ACCESSWIRE / September 17, 2024 / Applied DNA Sciences, Inc. (NASDAQ:APDN) ("Applied DNA" or the "Company"), a leader in PCR-based DNA technologies, today announced it has received a ...

Neopyropia is an important economic macroalga and is one of the main macroalgae cultivation species in China, Japan, South Korea and other countries ...

Applied DNA Sciences, Inc. (NASDAQ:APDN) (Applied DNA), a leader in PCR-based DNA technologies, today announced that on September 17, 2024, it received a notification letter (the “Notification Letter” ...

RNA modulates transcription factor binding to DNA, though the subsequent effect on transcription remains unclear. The study ...

Allows identification of pathogenic organisms that are difficult to culture by detecting their genetic material, RNA. Risks are usually minimal and vary depending on the sample collected. A real-time ...

Thanks to the emergence of immunosensors for HBV and HCV detection. The global market for Hepatitis B and C diagnostics is ...