The enzyme protein kinase N (PKN) has been implicated in a signaling cascade that causes heart fibroblast activation. A group ...

An increasing number of small-molecule protein kinase inhibitors are being developed and extensively tested for specificity against a panel of human kinases and in animal models of chronic ...

近年来，人们越来越注重健康和长寿，大多数人都知道运动对于保持身体健康的重要性。 然而，你可能惊讶地发现，过度的锻炼有时会对身体产生负面影响，甚至加速衰老的过程。 最近，一位著名的医生提醒人们，有些运动方式并不是强身健体的良方。 反而可能对身体造成伤害 ...

In a study published in Advanced Functional Materials, a research team from the Shanghai Institute of Materia Medica (SIMM) ...

2018年8月20日，济宁医学院附属滕州市中心人民医院妇产科的Jing Dong (第一作者) & Maoxiu Wang (第一作者) & Shujuan Yao (通讯作者 音译 姚淑娟)在Oncology Letters (中科院四区 IF=2 ...

心力衰竭（简称心衰）是各种心脏疾病发展的终末阶段，在目前最优化的治疗策略情况下，心衰患者的入院率、死亡率仍然居高不下。RNA结合蛋白是多种心血管疾病的调节因子，RNA解旋酶（dead-box helicase 5，DDX5）是许多RNA的主要调节因子 ...

As society ages, the number of patients with heart failure is rapidly increasing. Excessive growth of fibrotic tissue in the ...

Scientists found the molecule KIBRA works with PKMzeta to form long-term memories by tagging certain synapses, opening potential for memory-related therapies.

The excessive cosolute densities in the intracellular fluid create a physicochemical condition called macromolecular crowding (MMC). Intracellular MMC entropically maintains the biochemical ...

What sets this supplement apart is its mechanism of action. Berberine activates an enzyme called AMP-activated protein kinase (AMPK), which is central to cellular energy homeostasis. By influencing ...

GlobalData’s report assesses the drugs in the Myotonin Protein Kinase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.