The orderly execution of apoptosis is orchestrated by an evolutionarily conserved paradigm from worms to humans (Fig. 1). There are two major apoptotic pathways known to date, initiated by either ...

本文发表后，一位热心的读者向编辑指出，第3763页图1D中显示的某些细胞凋亡测定数据，与另一篇由不同研究机构的不同作者以不同形式提交发表的文章（图3A）中的数据惊人地相似。鉴于上述有争议的数据在提交给《 Molecular Medicine ...

Apoptosis, a process important for clearing damaged or infected cells, is the induction of cell suicide and can be triggered by either intrinsic cues or activation of the relevant pathways by ...

2020年1月20日，河北医科大学外科系在Oncotargets and Therapy（中科院四区 IF=2.7）刊上在线发表题为 "Silencing of LncRNA Metastasis-Associated Lung ...

综上，研究揭示了微塑料导致脱发的潜在机制，微塑料会诱导氧化应激水平，导致毛囊细胞细胞凋亡，进而导致毛囊内细胞间紧密连接受损，从而导致脱发。值得注意的是，老化的微塑料具有更强的毒性。

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

occurs either by degradation of sphingomyelin or by de novo synthesis. The quality and quantity of the ceramide response, in combination with other signals, determines whether adaptation or apoptosis ...

Recent research addresses this gap by demonstrating that caspase-2 directly processes BID, initiating the mitochondrial pathway of apoptosis. Moreover, the team discovered HUHS015, a compound that ...

The primary interest of our lab is to investigate the molecular mechanisms of apoptosis and how they impact human health and disease ... in combination with our spinning disk confocal microscope to ...

The pathways diagram (Academic career pathway diagram (PDF, 89kB)) shows the three pathways and roles, including accepted progression and promotion routes.‌‌ The clinical career pathways are sub-sets, ...

Complementary education pathways are programmes, including scholarships, that facilitate the movement of persons in need of international protection to a safe third country for the purpose of higher ...