谈及癌症转移，一句话总结就是一个巴掌拍不响。这是纪念斯隆-凯特琳癌症中心（MSK）研究人员领导的一项新研究的主要发现之一：TGF-β和RAS信号通路共同促进了肺腺癌的扩散，而肺腺癌是全球癌症死亡的主要原因。近日，一篇发表在国际杂志 Cell 上题为 “TGF-β and RAS jointly unmask primed enhancers to drive metastasis” ...

demonstrated that irinotecan plus oxaliplatin (IROX ... IROX does not change, but enriches the treatment algorithm of advanced colorectal cancer at the second-line level. The primary end point ...

引言作为全球范围内癌症相关死亡的主要元凶之一，结直肠癌的发病率呈现出随年龄增长而攀升的趋势。对于老年患者而言，其治疗复杂性不仅在于结直肠癌本身，还常伴随有年龄相关的器官功能衰退及合并症，这些因素共同影响着患者的治疗耐受性和药物选择。奥沙利铂因其显著的 ...

肝癌局部介入治疗手段多种多样，在肝癌综合治疗中发挥着不可替代的作用。其中经肝动脉化疗栓塞（TACE）是全球公认的肝癌非手术切除的首选治疗方式，而经肝动脉灌注化疗（HAIC）是治疗肝癌的另一种有效介入手段。目前国内外各大指南对 TACE、HAIC ...

Oxaliplatin is a third-generation platinum compound that was licensed for adjuvant treatment in combination with 5-FU and leucovorin in metastatic CRC in the EU since 1999 and in the USA since 2002.

Oxaliplatin belongs to a group of medicines ... Your doctor will take all the precautions need to reduce the side effects of treatment. Ask your doctor if you have any questions about why this ...

[24–26] According to this hypothesis, high TS levels may be associated with decreased benefit from 5-FU treatment, including decreased response, increased overall mortality and increased risk of ...

Trifluridine–tipiracil with bevacizumab is recommended, within its marketing authorisation, for treating metastatic colorectal cancer in adults who have had 2 lines of treatment (including ...

Currently, if a patient gets peripheral neuropathy during treatment, then the dose of oxaliplatin, for instance, has to be reduced or even stopped. Potentially, this means we are not going to control ...

Even if outbreaks of acne cannot be eliminated, conventional treatment can provide relief. The best treatments inhibit sebum production, limit bacterial growth, encourage shedding of skin cells to ...