Research Interests: Somatic Stem Cells and Aging, Genetic Mechanisms of Stem Cell Maintenance, Therapeutic Approaches to Tissue Rejuvenation, Mouse Models of Hair Graying, Melanocyte Stem Cells and ...
They discovered that ALX3, a transcription factor, binds to the promoter and represses MITF, a known regulator of melanocyte differentiation. To see if this newly discovered mechanism controlling ...
However, in this case, the experiments revealed something puzzling: The response differed between males and females. Initially unaware of the sex differences, the researchers sometimes observed a lot ...
Our lab uses human iPS and ES cells for modeling human disorders of the brain and peripheral nervous system such as Parkinson’s disease, familial dysautonomia, Herpes Simplex encephalitis and ...