The JAK2 protein is particularly important for controlling blood cell production from hematopoietic (blood-forming) stem ...

8 月 22 日，邦顺制药宣布，其开发的 1 类新药、JAK2 抑制剂邦瑞替尼 (OB756)的新药上市申请获得 CDE 受理，用于治疗中高危骨髓纤维化患者，这也是邦顺制药首个提交 NDA 的核心管线。Insight 数据库显示，邦瑞替尼也是首个在国内申报上市的选择性 JAK2 单靶点抑制剂。

Another 45 years passed before the discovery of a first genetic driver of non-Ph MPNs, a mutation in the Janus kinase 2 (JAK2 ...

Although researchers do not know the exact cause of MNPs, they associate them with certain genetic changes, such as variations in the JAK2 gene. Risk factors can include exposure to radiation or ...

Video games are facing a growth problem. The three major consoles are finally working to reach a broader base of gamers.

Sep. 9, 2024 — Scientists developed a highly promising gene therapy to treat glaucoma -- a debilitating eye condition that can lead to complete vision loss, and which affects around 80 million ...

Future therapies could intervene at the gene level, to prevent blindness ... generation immunotherapies leveraging synthetic biology. Jak Knowles, co-founder and CEO at Affini-T Therapeutics ...

View full profile. Learn about our editorial policies. The most basic unit of a specific ontology is a “term,” which refers to an attribute used to describe a specific gene function or product. 3 GO ...