Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...
In our laboratory, we delve into the intricate mechanisms employed by intestinal cells to secure the vital nutrients and metabolic resources essential for preserving intestinal stem cell fate and ...
Thus, in 2018, they observed that during fasting, intestinal stem cells begin to use lipids as an energy source, instead of carbohydrates. They also demonstrated that this process led to a ...
Researchers at Baylor College of Medicine, the University of Michigan and collaborating institutions have discovered that inflammation in the gut leaves long-term marks on intestinal stem cells ...
In humans, while stem cell proliferation at the molecular level is relatively well-understood, exhaustion remains largely a mystery. Previously, Sa Kan Yoo at RIKEN BDR identified how intestinal ...