The recent WHO classification has a category of acute myeloid leukemia not otherwise categorized, which includes acute erythroid leukemia (M6) of two subtypes: M6a-erythroleukemia (erythroid ...

Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice. Leukemia. 2020.View in PubMed Challen GA, Goodell MA. Clonal hematopoiesis: ...

The technology accurately detects the presence of these gene fusions in acute promyelocytic leukemia ... Radon, Even at Levels Below EPA Guideline for Mitigation, Is Linked to Childhood Leukemia Sep.

a AML = acute myelogenous leukemia. b Percentages do not total 100 because of rounding. c Significantly different from the corresponding value for the gemtuzumab ozogamicin group (p < 0.001).

More information: Andrew Stiff et al, Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia, Nature Genetics (2024). DOI: 10.1038/s41588 ...

However, translating this success to acute myeloid leukemia (AML) has proven difficult. Researchers at the University of Pennsylvania investigated the use of patient-derived anti-CD123 CAR T cells ...

Acute Myeloid Leukemia (AML) remains one of the most challenging hematological malignancies to treat, with relapse and refractory cases continuing to pose significant hurdles. Traditional ...

and cause leukemia. Trisomy 21 alters chromatin (DNA in packed form). Ts21 HSCs are primed for the erythroid lineage by chromatin modification. The reshaping allows transcription factors such as ...

Acute chest syndrome is a serious complication of sickle cell disease. It involves symptoms like chest pain, cough, or fever and can be life threatening if not treated promptly. Sickle cell ...